Priming with intranasal lactobacilli prevents Pseudomonas aeruginosa acute pneumonia in mice
Abstract Background Increasing resistance to antibiotics of Pseudomonas aeruginosa leads to therapeutic deadlock and alternative therapies are needed.We aimed to evaluate the effects of Lactobacillus clinical isolates in vivo, through intranasal administration on a murine model of Pseudomonas aeruginosa pneumonia.Results We screened in vitro 50 pul